Tributyrin is produced via esterification where 3 butyric acid is attached to a glycerol to form tributyrin. Tributyrin has a low melting point. It appears as clear oily liquid with odourless characteristics.
Tributyrin, being a triacylglycerol, is relatively stable and can release its butyric acid gradually in the intestine when digested by pancreatic lipase. It is also non-volatile at room temperature, so it is generally not coated.
When butyric acid enters the proximal small intestine, it will dissociate into butyrate and hydrogen ions. Here, butyric acid is readily absorbed by enterocytes via passive diffusion and used to increase villus length and cells turnover.
- Provides energy to enteric cells
- Increases villi growth
- Repairs damaged colon epithelial cells
- Improves digestive function and physiological barrier function of intestinal tract.
- Nutrient digestibility is improved
- Regulates gut microbiota
- Inhibits intestinal inflammation
- Improves flock/herd uniformity